Texans strike early on MNF as C.J. Stroud fires a 29-yard dart to Nico Collins for Houston’s first TD, signaling a potential resurgence after Week 1’s slow start. DeMeco Ryans explains that the opener’s struggles came from game script, not talent, and the Stroud–Collins connection looks like it could become a weekly staple. Collins finished 2024 with 1,006 yards on 68 receptions and seven TDs, and the offense now leans on sustaining that pace.

Fantasy takeaway: Collins looks primed for strong target volume, Stroud’s development boosts multiple Texans options, while Mayfield’s praise of Houston’s edge duo Will Anderson and Danielle Hunter hints at a growing Texans-dominant defense and a more complete team entering the schedule.

Jalen Pitre's rib injury tests Houston's nickel defense in the MNF clash with Tampa Bay. If he rests or is limited, Derek Stingley and Kamari Lassiter must lock outside while Tremon Smith and Jaylin Smith fill depth roles, heightening Tampa Bay's passing opportunities. Houston also battles missing receivers Christian Kirk, Braxton Berrios, and center Jake Andrews, plus the absence of Joe Mixon, widening the Texans' offensive uncertainty. Tampa Bay, dealing with Luke Goedeke and Tristan Wirfs out, presses Charlie Heck into action on the right side, elevating the Buccaneers' pass protection risks.

Fantasy angles tilt toward volume and volatility. Stroud could see more targets if Houston's defense softens, while Mayfield may exploit any matchup edges with Houston’s thin back end. Will Anderson's rush becomes even more pivotal for Houston, and Danielle Hunter's presence adds to the edge pressure. Monitor Pitre's status as game time nears, since the depth players stepping up will shape weekly lineups and bets.